Magnesium Glycinate vs L-Threonate

Both forms of magnesium work. The right choice depends on your primary goal.

Quick Verdict

Magnesium Glycinate

Magnesium chelated with glycine. Glycine binds GABA-A receptors independently, creating a double calming effect. High bioavailability, gentle on digestion, approx $15-25 per month.

Magnesium L-Threonate

Developed to cross the blood-brain barrier more efficiently (Slutsky et al. 2010, Neuron). Liu et al. 2016 showed improved cognitive function in older adults over 12 weeks. Costs $50-80 per month.

Bottom Line

Start with magnesium glycinate for sleep and stress. Add L-Threonate if cognitive symptoms are your primary concern.

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